1. Propolis, which is well tolerated with rare incidents of allergy and no toxicity, is excellent for burn management, enhancing skin cell proliferation, activation, and growth capacity.
2. Propolis is normally utilized in the hive to coat the inner walls, to shelter from the entrance of intruders, such as snakes and lizards, or against wind and rain, and to prevent fungi and bacteria growth.
3.A bee’s colony is able to collect from 150 to 200 g of propolis in 1 year; however, some colonies collect less than that.
4.Aristotle has coined the word propolis from the Greek words pro (before) and polis (city), meaning, before the city or defender of the city. Aristotle showed a remarkably accurate and detailed knowledge of propolis.
5.The positive activities of propolis are more numerous in tropical regions than in temperate climates, reproducing the richer vegetal diversity observed in the former.
6.Propolis collected from many countries (such as China, Korea, Croatia, New Zealand, and Africa) showed chemical composition similar to poplar. In fact, poplar tree is a typical tree in Europe and is used to name the common type of propolis.
7.The positive biological activity of propolis with respect to the human body largely results from the anti-oxidative effects of polyphenols.
8.Propolis also display anti-inflammatory properties in both acute and chronic inflammatory processes, and this is principally due to its large content of polyphenol compounds.
9.Propolis also contains active compounds which are known to promote cell proliferation or apoptosis. Among them, there are caffeic acid (image above), caffeic phenyl ester, artepillin C, quercetin, resveratrol, galangin, and genistein.
10. In-vitro tests (tests conducted in a lab) have demonstrated that some propolis flavonoids inhibit the development of lung cancer and oral cancer, as well as skin, esophagus, stomach, colorectal, prostate, and breast cancers.
11.Flavonoids are considered as valuable natural compounds not only because they avoid rapid blood sugar rises in the serum, but also because they are able to shelter diabetics from the complications of this metabolic disorder.
12.The results confirm the importance of phenolic acids for propolis antibacterial activity, and the significance of poplar as a propolis source, which offers the most efficient defense for hives against bacteria. We use Propolis in our Anti-Spot Cream and Anti-Redness Cream with great results.
13.Banksota et al. compared the cytotoxic, hepatoprotective (ability to protect the liver), and free radical scavenging activity of propolis from Brazil, Peru, The Netherlands, and China. The authors found that propolis from The Netherlands and China possessed the strongest cytotoxic activity; while almost all samples possessed significant liver protecting properties.
14.Propolis extracts from Argentina, Australia, China, Hungary, and New Zealand had relatively strong antioxidant activities and were associated with the total polyphenol and flavonoid contents.
15.A recent report suggested that propolis is able to quench free radicals in skin. This outcome of propolis on free radicals in the epidermis is the source of safety of its application in the therapy of burn wounds.
16. Other findings reveal that propolis speed up the burned tissue repair by stimulation of the wound bed matrix remodeling, proposing that the observed changes in extracellular matrix may be connected with the ability of its flavonoid compounds to reduce lipid peroxidation and to prevent cells from dying.
17.Biological activities of propolis on wound repair and tissue regeneration might be correlated to its antimicrobial, anti-inflammatory, and immumonodulatory properties. (This is why we find our Wound Healing Ointment to be so effective at healing burns, blisters, cuts, grazes, eczema, dermatitis, sun burn, cold sores and pimples).
18.Propolis has demonstrated some in vitro antimicrobial activity, in particular against Gram-positive (Staphylococci and Streptococci spp.) and Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, and Pseudomonas aeruginosa), Helicobacter pylori, protozoa (Trypanosoma cruzi), fungi (Candida albicans), and viruses (such as HIV, Herpes viruses, or influenza viruses).
19. Antimicrobial properties of propolis are essentially due to the flavonoid content and in particular to the presence of pinocembrin, galangin, and pinobanksin. Pinocembrin also exhibits antifungal properties. Other compounds with well-established effects are ester of coumaric and caffeic acids.
20. This study showed that the minimum inhibitory concentration or MIC (minimum concentration required to inhibit growth of E.Coli) for Propolis was 0.55%. We make our Wound Healing Ointment to be twice that percentage. The minimum concentration of Propolis required to inhibit growth of Staph. Aureus was 0.27%. Our Wound Healing Ointment is four times this amount.
When you compare this to the much higher minimum percentage required for honey to inhibit S.Aureus at 37.5% and the fact that honey did not have any inhibitory effect on E.Coli, Propolis is truly the bees knees.